I am currently the chair and full professor in the Department of Neurobiology and Physiology, School of Dentistry, and the director of Medical Research Center (MRC) in Seoul National University. My work has focused on understanding of molecular and cellular mechanisms of physiological nociception, and how their changes transit to chronic pain in pathological conditions. I have been studying these topics through multidisciplinary approaches- from gene to behavior, and from molecular level to systemic level, and recently extending to the cognitive level. More specifically, my research goal is to better understand role of neuro-immune interaction in the peripheral neuropathy and the pathophysiology of chronic pain, and thereby to find a novel and mechanism-oriented therapeutics for targeting intractable chronic pain conditions. I’ve published my works in Cell, Neuron, J Neuroscience, Pain, Journal of Biological Chemistry, Scientific Reports, etc. As a dentist, I have been also trying to understand molecular and cellular mechanism underlying three hypotheses which explain tooth pain hypersensitivity, and have published 15 papers in Journal of Dental Research. I have received excellence in research award from Korean Physiological Society (2012), Korea Society for Brain and Neural Sciences (2019), and Seoul National University (2020).
Research & Clinical Focus
Physiological pain mechanism
Neuropathic pain and neuro-immune interaction
Novel therapeutics for Chronic Pain